n  Education Background(學歷背景)

B.S. Ch.E. Feng Chia University, 2001

M.S. Ch.E. National Taiwan University of Science and Technology, 2003

Ph. D. Ch.E. National Taiwan University of Science and Technology, 2007

n  Research Topic (研究方向)

Our research has focused on genetic metabolism, including its biochemistry and regulation. We use genetic engineering and metabolic engineering to construct microorganisms to produce pharmaceutical proteins and next generation biofuels. Currently, our projects include engineering proteins, biochemical pathways for CO2 fixation, and production of fuels and chemicals from fatty acids. Our ultimate goal us to use biochemical methods to replace petroleum processing and pharmaceutical proteins production. The key research topics are listed: 

I.          A novel flocculant design and its application.

II.        Pharmaceutical proteins production by using Secretory E. coli system

III.     High value products production

IV.     Bacterial mutation system

V.        …

n  Recent 5-years Research Topic(近五年研究計畫)

1.          [環保型陽離子凝集劑之試量生產製程開發]， Formosa Biomedical Technology Corp，2016/01/01~2016/06/30

2.          [特定碳數脂肪酸基因工程及發酵測試]，Institute of Nuclear Energy Research， 2015/05/01~2015/11/30

3.          [Immunotherapy of hepatocellular carcinoma by alpha-fetoprotein DNA vaccination]，sponsored by Ministry of Science and Technology, R.O.C.，MOST 103-2622-E-131-003-CC3

4.          [Biosynthesis of Nylon precursor Dodecanedioic acid by using genetically modified Yarrowia lipolytica] ，sponsored by Ministry of Science and Technology, R.O.C.，MOST 103-2221-E-131-022-

5.          [高二元酸轉化率菌種篩選菌種改良研究]，CPC Corporation, Taiwan， 2014/08/25-2016/02/22

6.          [Biosynthesis of Long-Chain Dicarboxylic Acid Monomers by using genetically modified Yarrowia lipolytica (I)] ，sponsored by Ministry of Science and Technology, R.O.C.，MOST 102-2221-E-131-020-

7.          [基因重組大腸桿菌表現系統建構]，Yungshin Pharm Ind. Co. Ltd.， 2014/04/01~2015/03/31

8.          [PP碳纖複材漿液製作技術]，Formosa Plastics Corporation，2014/04/01~2015/03/31

9.          [Avian Influenza Vaccines production in the aquatic plant Lemna minor] ，sponsored by Ministry of Science and Technology, R.O.C.，MOST 101-2221-E-131-033-

10.      [High-yielding zeaxanthin-producing strain and its bioprocess development] ，sponsored by Ministry of Science and Technology, R.O.C.，MOST 101-2622-E-131-002-CC2

11.      [免疫抑制劑之菌種改良研究(I-VI)]，Yungshin Pharm Ind. Co. Ltd.， 2013/03/01~2016/02/28

12.      [環脂肽類抗生素之菌種改良研究(I-IV)]，Yungshin Pharm Ind. Co. Ltd.， 2013/12/01~2015/11/30

13.      [Manipulation of microalgal lipid content by metabolically engineered eukaryotic microalgae] ，sponsored by Ministry of Science and Technology, R.O.C.，MOST 100-2221-E-131-010-

14.      [利用表面蛋白表現技術提升腸道細胞對乳酸菌疫苗之吸附性]，教育部區域產學-Lihpao Life Science Corp.，2014/01/20~2014/12/31